Endocrine Abstracts

Background: An adrenal incidentaloma is defined as an adrenal mass larger than 1 cm, detected on imaging performed for an indication other than evaluation of adrenal disease. Following the European Society of Endocrinology clinical practice guideline, assessment of malignancy by imaging and hormone excess should be done simultaneously(1). To investigate whether an adrenal mass is functionally active, a thorough clinical examination is required, extended with a 1mg o...

Background: Cystic fibrosis (CF) is a genetic disorder in which a dysfunctional cystic fibrosis transmembrane regulator (CFTR) chloride channel can result in multimorbidity, including severe respiratory disease and reduced pancreatic exocrine secretion and diabetes. Recently, CFTR modulator therapy, has emerged with the potential of improving respiratory function and remission of diabetes. The effect of CFTR modulator therapy on pancreatic function in patients without preexist...